Papers

2024
295.
Noh, I.; Guo, Z.; Wang, R.; Zhu, A.; Krishnan, N.; Mohapatra, A.; Gao, W.; Fang, R.; Zhang, L.* "Modular functionalization of cellular nanodiscs enables targeted delivery of chemotherapeutics into tumors", Journal of Controlled Release 2024, in press.
294.
Nandhakumar, P.; Sun, L.; Li, Z.; Cheung, C.; Nguyen, L.; Ding, S.; Gao, W.; Zhang, L.*, Wang, J. "Biomimetic cell membrane layers for the detection of insulin and glucagon", Analytical Chemistry, 2024, in press.
293.
Kai, M.; Shen, W.; Wang, D.; Yu, Y.; Zhang, J.; Sun, L.; Fang, R.; Gao, W.; Zhang, L.* "Aptamer-encapsulated cellular nanoparticles for neurotoxin neutralization", Advanced Healthcare Materials 2024, in press.
292.
Yu, Y.; Silva-Ayala, D.; Zhou, Z.; Peng, Y.; Fang, R.; Gao, W.; Griffiths, A.; Zhang, L.* "Cellular nanoparticles treat coronavirus infection in vivo", Nano Letters 2024, 24, 15136-15141. [link]
291.
Mundaca-Uribe, R.; Askarinam, N.; Fang, R.; Zhang, L.*; Wang, J. "Towards multifunctional robotic pills", Nature Biomedical Engineering 2024, 8, 1334-1346. [link]
290.
Zhang, J.; Feng, K.; Shen, W.; Gao, W.; Zhang, L.* "Research advances of cellular nanoparticles as multiplex countermeasures", ACS Nano 2024, 18, 30211-30223. [link]
289.
Guo, Z.; Zhu, A.; Fang, R.; Zhang, L.* "Viral and nonviral nanocarriers for in vivo CRISPR-based gene editing", Nano Research 2024, 17, 8904-8925. [link]
288.
Wang, D.; Sun, L.; Shen, W.; Haggard, A.; Yu, Y.; Zhang, J.; Fang, R.; Gao, W.; Zhang, L.* "Neuronal membrane-derived nanodiscs for broad-spectrum neurotoxin detoxification", ACS Nano 2024, 18, 25069-25080. [link]
287.
Zhou, Z.; Mukundan, N.; Zhang, J.; Wu, M.; Zhang, Q.; Wang, D.; Fang, R.; Gao, W.; Zhang, L.* "Macrophage-mimicking cellular nanoparticles scavenge proinflammatory cytokines in specimens of patients with inflammatory disorders", Advanced Science 2024, 11, 2401423. [link]
286.
Guo, Z.; Zhu, A.; Wei, X.; Jiang, Y.; Yu, Y.; Noh, I.; Gao, W.; Fang, R.; Zhang, L.* "A genetically engineered neuronal membrane-based nanotoxoid elicits protective immunity against neurotoxins", Bioactive Materials 2024, 38, 321-330. [link]
285.
Li. Z.; Duan,Y.; Zhang, F.; Luan, H.; Shen, W.; Yu, Y.; Xian, N.; Guo, Z.; Zhang, E.; Yin, L.; Fang, R.; Gao, W.; Zhang, L.*; Wang, J. "Biohybrid microrobots regulate colonic cytokine levels and modulate epithelium layer restoration in inflammatory bowel disease", Science Robotics 2024, 9, eadl2007. [link] [highlight]
284.
Krishnan, N.; Fang, R.; Zhang, L.* "Rapid functionalization of cell membrane-coated nanoparticles using a modular approach", Clinical and Translational Medicine 2024, 14, e1721. [link]
283.
Kai, M.; Shen, W.; Yu, Y.; Wang, D.; Zhang, J.; Wang, S.; Fang, R.; Gao, W.; Zhang, L.* "Dual-modal cellular nanoparticles for continuous neurotoxin detoxification", Nano Letters 2024, 24, 7515-7523. [link]
282.
Zhang, F.; Guo, Z.; Li, Z.; Luan, H.; Yu, Y.; Zhu, A.; Ding, S.; Gao, W.; Fang, R.; Zhang, L.*, Wang, J. "Biohybrid microrobots deliver drug-loaded nanoparticles to hinder the progression of lung metastasis", Science Advances 2024, 10, eadn6157. [link]
281.
Sun, L.; Wang, D.; Feng, K.; Zhang, J.; Gao, W.; Zhang, L.* "Cell membrane-coated nanoparticles for targeting carcinogenic bacteria", Advanced Drug Delivery Reviews 2024, 209, 115320. [link]
280.
Yu, Y.; Peng, Y.; Shen, W.; Zhou, Z.; Kai, M.; Gao, W.; Zhang, L.* "Hybrid cell membrane-coated nanoparticles for biomedical applications", Small Structures 2024, 5, 2300473. [link]
279.
Sun, L.; Yu, Y.; Peng, Y.; Wang, D.; Wang, S.; Noh, I.; Fang, R.; Gao, W.; Zhang, L.* "Platelet membrane-derived nanodiscs for neutralization of endogenous autoantibodies and exogenous pathogens", Small 2024, 20, 2308327. [link]
278.
Wang, S.; Wang, D.; Shen, W.; Kai, M.; Yu, Y.; Peng, Y.; Xian, N.; Fang, R.; Gao, W.; Zhang, L.* "Protein-loaded cellular nanosponges for dual-biomimicry neurotoxin countermeasure", Small 2024, 20, 2309635. [link]
277.
Krishnan, N.; Jiang, Y.; Zhou, J.; Mohapatra, A.; Peng, F.; Duan, Y.; Holay, M.; Chekuri, S.; Guo, Z.; Gao, W.; Fang, R.; Zhang, L.* "A modular approach to enhancing cell membrane-coated nanoparticle functionality using genetic engineering", Nature Nanotechnology 2024, 19, 345-353. [link]
276.
Zhang, F.; Li, Z.; Chen, C.; Luan, H.; Fang, R.; Zhang, L.*; Wang, J. "Biohybrid microalgae robots: Design, fabrication, materials and applications", Advanced Materials 2024, 36, 2303714. [link]
2023
275.
Duan, Y.; Zhou, J.; Zhou, Z.; Zhang, E. Yu, Y.; Krishnan, N.; Silva-Ayala, D.; Fang, R.; Griffiths, A.; Gao, W.; Zhang, L.* "Extending the in vivo residence time of macrophage membrane-coated nanoparticles through genetic modification", Small 2023, 19, 2305551. [link]
274.
Fang, R.; Zhang, L.* "Biohybrid nanoparticles for treating arthritis", Nature Nanotechnology 2023, 18, 1387-1388. [link]
273.
Ai, X.; Wang, D.; Noh, I.; Duan, Y.; Zhou, Z.; Mukundan, N.; Fang, R.; Gao, W.; Zhang, L.* "Glycan-modified cellular nanosponges for enhanced neutralization of botulinum toxin", Biomaterials 2023, 302, 122330. [link]
272.
Guo, Z.; Noh, I.; Zhu, A.; Yu, Y.; Gao, W.; Fang, R.; Zhang, L.* "Cancer cell membrane nanodiscs for antitumor vaccination", Nano Letters 2023, 23, 7941-7949. [link]
271.
Kai, M.; Wang, S.; Gao, W.; Zhang, L.* "Designs of metal-organic framework nanoparticles for protein delivery", Journal of Controlled Release 2023, 361, 178-190. [link]
270.
Duan, Y.; Zhang, E.; Fang, R.; Gao, W.; Zhang, L.* "Capsulated cellular nanosponges for the treatment of experimental inflammatory bowel disease", ACS Nano 2023, 17, 15893-15904. [link]
269.
Guo, Z.; Zhou, J.; Yu, Y.; Krishnan, N.; Noh, I.; Zhu, A.; Borum, R. Gao, W.; Fang, R.; Zhang, L.* "Immunostimulatory DNA hydrogel enhances protective efficacy of nanotoxoids against bacterial infection", Advanced Materials 2023, 35, 2211717. [link]
268.
Pihl, J.; Clausen, T.; Zhou, J.; Krishnan, N.; Madsen, M.; Gustavesson, T.; Dagil, R.; Daugaard, M.; Choudhary, S.; Foged, C.; Esko, J.; Zhang, L.; Fang, R.; Salanti, A. "A malaria biomimetic for tumor targeted drug delivery", ACS Nano 2023, 17, 13500-13509. [link]
267.
Zhou, Z.; Kai, M.; Wang, S.; Wang, D.; Peng, Y.; Yu, Y.; Gao, W.; Zhang, L.* "Emerging nanoparticle designs against bacterial infections", WIREs Nanomedicine & Nanobiotechnology 2023, 15, e1881. [link]
266.
Krishnan, N.; Fang, R.; Zhang, L.* "Cell membrane-coated nanoparticles for the treatment of cancer", Clinical and Translational Medicine 2023, 13, e1285. [link]
265.
Mundaca-Uribe, R.; Holay, M.; Abbas, A.; Askarinam, N.; Sage-Sepulveda, J.; Kubiatowicz, L; Fang, R.; Zhang, L.*, Wang, J. "A microstirring oral pill for improving the glucose-lowering effect of metformin", ACS Nano 2023, 17, 9272-9279. [link]
264.
Guo, Z.; Zhu, A.; Fang, R.; Zhang, L.* "Recent developments in nanoparticle-based photo-immunotherapy for cancer treatment", Small Methods 2023, 7, 2300252. [link]
263.
Sun, L.; Wang, D.; Noh, I.; Fang, R.; Gao, W.; Zhang, L.* "Synthesis of erythrocyte nanodiscs for bacterial toxin neutralization", Angewandte Chemie International Edition 2023, 62, e202301566. [link] [journal cover]
262.
Krishnan, N.; Peng, F.; Mohapatra, A.; Fang, R.; Zhang, L.* "Genetically engineered cellular nanoparticles for biomedical application", Biomaterials 2023, 296, 122065. [link]
261.
Wang, S.; Wang, D.; Kai, M.; Shen, W.; Sun, L.; Gao, W.; Zhang, L.* "Design strategies for cellular nanosponges as medical countermeasures", BME Frontiers 2023, 4, 0018. [link]
260.
Fang, R.; Zhang, L.* "Inhalable mRNA nanoparticles", Nature Materials 2023, 22, 278-279. [link]
259.
Duan, Y.; Wang, D.; Wang, S.; Zhou, Z.; Komarla A.; Zhou, J.; Zhang, Q.; Ai, X.; Gao, W.; Zhang, L.* "Cell membrane-coated nanoparticles and their biomedical applications", Encyclopedia of Nanomaterials 2023, 3, 519-542. [link]
258.
Bjanes, E.; Zhou, J.; Qayum, T.; Krishnan, N.; Zurich, R.; Menon, N.; Hoffman, A.; Fang, R.; Zhang, L.*, Nizet, V. "Outer membrane vesicle-coated nanoparticle vaccine protects against Acinetobacter baumannii pneumonia and sepsis", Advanced NanoBiomed Research 2023, 3, 2200130. [link]
257.
Noh, I.; Guo, Z.; Zhou, J.; Gao, W.; Fang, R.; Zhang, L.* "Cellular nanodiscs made from bacterial outer membrane as a platform for antibacterial vaccination", ACS Nano 2023, 17, 1120-1127. [link]
256.
Fang, R.; Gao, W.; Zhang, L.* "Targeting drugs to tumours using cell membrane-coated nanoparticles", Nature Reviews Clinical Oncology 2023, 20, 33-48. [link] [journal cover]
2022
255.
Zhang, F.; Li, Z.; Duan, Y.; Luan, H.; Yin, L.; Guo, Z.; Chen, C.; Xu, M.; Gao, W.; Fang, R.; Zhang, L.*, Wang, J. "Extremophile-based biohybrid micromotors for biomedical operations in harsh environments", Science Advances 2022, 8, eade6455. [link]
254.
Kubiatowicz, L.; Mohapatra, A.; Krishnan, N.; Fang, R.; Zhang, L.* "mRNA nanomedicine: design and recent applications", Exploration 2022, 2, 20210217. [link]
253.
Holay, M.; Krishnan, N.; Zhou, J.; Duan, Y.; Guo, Z.; Gao, W.; Fang, R.; Zhang, L.* "Single low-dose nanovaccine for long-term protection against anthrax toxins", Nano Letters 2022, 22, 9672-9678. [link]
252.
Wang, D.; Ai, X.; Duan, Y.; Xian, N.; Fang, R.; Gao, W.; Zhang, L.* "Neuronal cellular nanosponges for effective detoxification of neurotoxins", ACS Nano 2022, 16, 19145-19154. [link]
251.
Zhang, F.; Zhuang, J.; Li, Z.; Gong, H.; Bsteban-Fernandez de Avila, B.; Duan, Y.; Zhang, Q.; Zhou, J.; Yin, L.; Karshalev, E.; Gao, W.; Nizet, V.; Fang, R.; Zhang, L.*; Wang, J. "Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia", Nature Materials 2022, 21, 1324-1332. [link]
250.
Vargas, E.; Zhang, F.; Hassine, A.; Montiel, V.; Mundaca-Uribe, R.; Nandhakumar, P.; He, P.; Guo, Z.; Zhou, Z.; Fang, R.; Gao, W.; Zhang, L.*; Wang, J. "Using cell membrane as recognition layers to construct ultrasensitive and selective bioelectronic affinity sensors", Journal of the American Chemical Society 2022, 144, 17700-17708. [link]
249.
Zhang, F.; Li, Z.; Duan, Y.; Abbas, A.; Mundaca-Uribe, R.; Yin, L.; Luan, H.; Gao, W.; Fang, R.; Zhang, L.*, Wang, J. "Gastrointestinal tract drug delivery using algae motors embedded in a degradable capsule", Science Robotics 2022, 7, eabo4160. [link]
248.
Zhou, J.; Ventura, C.; Yu, Y.; Gao, W.; Fang, R.; Zhang, L.* "Biomimetic neutrophil nanotoxoids elicit potent immunity against Acinetobacter baumannii in multiple models of infection", Nano Letters 2022, 22, 7057-7065. [link]
247.
Zhou, J.; Krishnan, N.; Guo, Z.; Ventura, C.; Holay, M.; Zhang, Q.; Wei, X.; Gao, W.; Fang, R.; Zhang, L.* "Nanotoxoid vaccination protects against opportunistic bacterial infections arising from immunodeficiency", Science Advances 2022, 8, eabq5492. [link]
246.
Zhou, J.; Miyamoto, Y.; Ihara, S.; Kroll, A.; Nieskens, N.; Tran, V.; Hanson, E.; Fang, R.; Zhang, L., Eckmann, L. "Co-delivery of antigens and adjuvant in polymeric nanoparticles coated with native parasite membranes induces protective mucosal immunity against Giardia lamblia", Journal of Infectious Diseases 2022, 226, 319-323. [link]
245.
Wang, S.; Kai, M.; Duan, Y.; Zhou, Z.; Fang, R.; Gao, W.; Zhang, L.* "Membrane cholesterol depletion enhances enzymatic activity of cell-membrane-coated metal-organic-framework nanoparticles", Angewandte Chemie International Edition 2022, 61, e202203115. [link] [journal cover]
244.
Krishnan, N.; Kubiatowicz, L.; Holay, M.; Zhou, J.; Fang, R.; Zhang, L.* "Bacterial membrane vesicles for vaccine applications", Advanced Drug Delivery Reviews 2022, 185, 114294. [link]
243.
Holay, M.; Zhou, J.; Park, J.; Landa, I.; Ventura, C.; Gao, W.; Fang, R.; Zhang, L.* "Organotropic targeting of biomimetic nanoparticles to treat lung diseases", Bioconjugate Chemistry 2022, 33, 586-593. [link]
242.
Wang, D.; Wang, S.; Zhou, Z.; Bai, D.; Zhang Q.; Gao, W.; Zhang, L.* "White blood cell membrane-coated nanoparticles: recent development and medical applications", Advanced Healthcare Materials 2022, 11, 2101349. [link]
241.
Johnson, D.; Zhou, J.; Kroll, A.; Fang, R.; Yan, M.; Xiao, C.; Chen, X.; Kline, J.; Zhang, L.; Zhang, D-E. "Acute myeloid leukemia cell membrane-coated nanoparticles for cancer vaccination immunotherapy", Leukemia 2022, 36, 994-1005. [link]
240.
Wang, S.; Wang, D.; Duan, Y.; Zhou, Z.; Gao, W.; Zhang, L.* "Cellular nanosponges for biological neutralization", Advanced Materials 2022, 34, 2107719. [link]
239.
Gu, Y.; Wang, C.; Kim, N.; Zhang, J.; Wang, T. M.; Stowe, J.; Nasiri, R.; Li, J.; Zhang, D.; Yang, A.; Hsu, L.; Dai, X.; Mu, J.; Lawence, N.; Liu, Z.; Lin, M.; Li, W.; Wang, C.; Gong, H.; Chen, Y.; Lei, Y.; Hu, H.; Li, Y.; Zhang, L.; Huang, Z; Zhang, X.; Ahadian, S.; Banik, P.; Zhang, L.; Jiang, X.; Burke, P.; Khademhosseini, A.; McCulloch, A.; Xu, S. "Three-dimensional transistor arrays for intra- and inter-cellular recording", Nature Nanotechnology 2022, 17, 292-300. [link]
238.
Zhang, F.; Mundaca-Uribe, R.; Askarinam, N.; Li, Z.; Gao, W.; Zhang, L.*, Wang, J. "Biomembrane-functionalized micromotors: biocompatible active devices for diverse biomedical applications", Advanced Materials 2022, 34, 2107177. [link]
237.
Zhou, J.; Ventura, C.; Fang, R.; Zhang, L.* "Nanodelivery of STING agonists against cancer and infectious diseases", Molecular Aspects of Medicine 2022, 83, 101007. [link]
236.
Park, J. H.; Mohapatra, A.; Zhou, J.; Holay, M.; Krishnan, N.; Gao, W.; Fang, R.; Zhang, L.* "Virus-mimicking cell membrane-coated nanoparticles for cytosolic delivery of mRNA", Angewandte Chemie International Edition 2022, 61, e202113671. [link]
2021
235.
Zhou, J.; Karshalev, E.; Mundaca-Uribe, R.; Bsteban-Fernandez de Avila, B.; Krishnan, N.; Xiao, C.; Ventura C.; Gong, H.; Zhang, Q.; Gao, W.; Fang, R.; Wang, J.; Zhang L.* "Physical disruption of solid tumors by immunostimulatory microrobots enhances antitumor immunity", Advanced Materials 2021, 33, 2103505. [link]
234.
Duan, Y.; Wang, S.; Zhang, Q.; Gao, W.; Zhang, L.* "Nanoparticle approaches against SARS-CoV-2 infection", Current Opinion in Solid State & Materials Science 2021, 25, 100964. [link]
233.
Krishnan, N.; Fang, R.; Zhang, L.* "Engineering of stimuli-responsive self-assembled biomimetic nanoparticles", Advanced Drug Delivery Reviews 2021, 179, 114006. [link]
232.
Ai, X.; Wang, D.; Honko, A.; Duan, Y.; Gavrish, I.; Fang, R.; Griffiths, A.; Gao, W.; Zhang, L.* "Surface glycan modification of cellular nanosponges to promote SARS-CoV-2 inhibition", Journal of the American Chemical Society 2021, 143, 17615-17621. [link]
231.
Campbell, G.; Zhuang, J.; Zhang, G.; Landa, I.; Kubiatowicz, L.; Dehaini, D.; Fang, R.; Zhang, L.; Spector, S. "CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kills HIV-1 infected cells", Theranostics 2021, 11, 9009-9021. [link]
230.
Kim, J-K.; Uchiyama, S.; Gong, H.; Zhang, L.; Nizet, V. "Engineered biomimetic platelet membrane-coated nanoparticles block Staphylococcus aureus cytotoxicity and protect against lethal systemic infection", Engineering 2021, 7, 1149-1156. [link]
229.
Guo, Z.; Kubiatowicz, L.; Fang, R.; Zhang, L.* "Nanotoxoids: biomimetic nanoparticle vaccines against infections", Advanced Therapeutics 2021, 4, 2100072. [link]
228.
Zhang, F.; Li, Z.; Yin, L.; Zhang, Q.; Askarinam, N.; Mundaca-Uribe, R.; Tehrani, F.; Karshalev E.; Gao, W.; Zhang, L.*; Wang, J. "ACE2 receptor-modified algae-based microrobot for removal of SARS-CoV-2 in wastewater", Journal of the American Chemical Society 2021, 143, 12194-12201. [link] [journal cover]
227.
Zhang, Q.; Zhou, J.; Zhou, J.; Fang, R.; Gao, W.; Zhang, L.* "Lure-and-kill macrophage nanoparticles alleviate the severity of experimental acute pancreatitis", Nature Communications 2021, 12, 4136. [link]
226.
Mundaca-Uribe, R.; Karshalev, E.; Bsteban-Fernandez de Avila, B.; Wei, X.; Nguyen, B.; Litvan, I.; Fang, R.; Zhang, L.*; Wang, J. "A microstirring pill enhances bioavailability of orally administered drugs", Advanced Science 2021, 8, 2100389. [link]
225.
Park, J. H.; Jiang, Y.; Zhou, J.; Gong, H.; Mohapatra, A.; Heo, J.; Gao, W.; Fang, R.; Zhang, L.* "Genetically engineered cell membrane-coated nanoparticles for targeted delivery of dexamethasone to inflamed lungs", Science Advances 2021, 7, eabf7820. [link]
224.
Miyamoto, Y.; Aggarwal, S.; Celaje, J.; Ihara, S.; Ang, J.; Land, K.; Wrischnik, L.; Zhang, L.; Fokin, V.; Eckmann, L. "Gold(I) phosphine derivatives with improved selectively as topically active drug leads to overcome 5-nitroheterocyclic drug resistance in Trichomonas vaginalis", Journal Medicinal Chemistry 2021, 64, 6608-6620. [link]
223.
Holay, M.; Guo, Z.; Pihl, J.; Heo, J.; Park, J.; Fang, R.; Zhang, L.* "Bacteria-inspired nanomedicine", ACS Applied Bio Materials 2021, 4, 3830-3848. [link]
222.
Ai, X.; Wang, S.; Duan, Y.; Zhang, Q.; Chen, M.; Gao, W.; Zhang, L.* "Emerging approaches to functionalizing cell membrane-coated nanoparticles", Biochemistry 2021, 60, 941-955. [link]
221.
Bahmani, B.; Gong, H.; Luk, B.; Haushalter, K.; DeTeresa, E.; Previti, M.; Zhou, J.; Gao, W.; Bui, J.; Zhang, L.; Fang, R.; Zhang, J. "Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors", Nature Communications 2021, 12, 1999. [link]
220.
Gong, H.; Zhang, Q.; Komarla, A.; Wang, S.; Duan, Y.; Zhou, Z.; Chen, F.; Fang, R.; Xu, S.; Gao, W.; Zhang, L.* "Nanomaterial biointerfacing via mitochondrial membrane coating for targeted detoxification and molecular detection", Nano Letters 2021, 21, 2603-2609. [link]
219.
Zhou, J.; Krishnan, N; Jiang, Y.; Fang, R.; Zhang, L.* "Nanotechnology for virus treatment", Nano Today 2021, 36, 101031. [link]
218.
Ai, X.; Duan, Y.; Zhang, Q.; Sun, D.; Fang, R.; Liu-Bryan, R.; Gao, W.; Zhang, L.* "Cartilage-targeting ultrasmall lipid-polymer hybrid nanoparticles for the prevention of cartilage degradation", Bioengineering & Translational Medicine 2021, 6, e10187. [link] [journal cover]
217.
Gao, W.; Zhang, L.* "Nanomaterials arising amid antibiotic resistance", Nature Reviews Microbiology 2021, 19, 5-6. [link]
2020
216.
Wang, S.; Duan, Y.; Zhang, Q.; Komarla, A.; Gong, H.; Gao, W.; Zhang, L.* "Drug targeting via platelet membrane-coated nanoparticles", Small Structures 2020, 1, 2000018. [link]
215.
Mundaca-Uribe, R.; Bsteban-Fernandez de Avila, B.; Holay, M.; Venugopalan, P.; Nguyen, B.; Zhou, J.; Abbas, A.; Fang, R.; Zhang, L.*; Wang, J. "Zinc microrocket pills: fabrication and characterization towards active oral delivery", Advanced Healthcare Materials 2020, 9, 2000900. [link]
214.
Zhang, G.; Campbell, G.; Zhang, Q.; Maule, E.; Hanna J.; Gao, W.; Zhang, L.; Spector, S. "CD4+ T cell mimicking nanoparticles broadly neutralize HIV-1 and suppress viral replication through autophagy", mBio 2020, 11, e00903-20. [link]
213.
Huang, N.; Fan, X.; Rivera, K.; Nguyen, T.; Zhou, J.; Luo, Y.; Gao, J.; Fang, R.; Yan, Z.; Chen, Z.; Zhang, L.; Zhong, S. "Natural display of nuclear-encoded RNA on the cell surface and its impact on cell interaction", Genome Biology, 2020, 21, 225. [link]
212.
Lipomi, D.; Fenning, D.; Ong, S. P.; Shah, N.; Tao, A.; Zhang, L. "Exploring frontiers in research and teaching: NanoEngineering and Chemical Engineering at UC San Diego", ACS Nano 2020, 14, 9203-9216. [link]
211.
Jiang, Y.; Krishnan, N.; Zhou, J.; Chekuri, S.; Wei, X.; Kroll, A.; Yu, C.; Gao, W.; Fang, R.; Zhang, L.* "Engineered cell membrane-coated nanoparticles directly present tumor antigens to promote anticancer immunity",  Advanced Materials 2020, 32, 2001808. [link]
210.
Zhang, Q.; Honko, A.; Zhou, J.; Downs, S.; Henao Vasquez, J.; Fang, R.; Gao, W.; Griffiths, A.; Zhang, L.* "Cellular nanosponges inhibit SARS-CoV-2 infectivity", Nano Letters 2020, 20, 5570-5574. [link]
Highlighted: Science Translational Medicine 2020, 12, eabd3078 (Editor's Choice). [link]
                    Forbes June 17, 2020. [link]
209.
Bsteban-Fernandez de Avila, B., Lopez-Ramirez, M.; Mundaca-Uribe, R.; Wei, X.; Ramirez-Herrera, D.; Karshalev, E.; Nguyen, B.; Fang, R.; Zhang, L.*, Wang, J. "Multi-compartment tubular micromotors towards enhanced localized active delivery", Advanced Materials 2020, 32, 2000091. [link]
208.
Zhang, Q.; Fang, R.; Gao, W.; Zhang, L.* "A biomimetic nanoparticle to 'lure and kill' phospholipase A2", Angewandte Chemie International Edition 2020, 59, 10461-10465. [link]
207.
Tang, S.; Zhang, F.; Gong, H.; Wei, F.; Zhuang, J.; Karshalev, E.; Bsteban-Fernandez de Avila, B., Huang, C.; Hu, Z; Zhou, Z.; Li, Z; Lu, Y.; Dong, H.; Fang, R.; Zhang, X.; Zhang, L.*, Wang, J. "Enzyme-powered Janus platelet micromotors for targeted therapeutic delivery", Science Robotics 2020, 5, eaba6137. [link]
Highlighted: Science Robotics 2020, 5, eabc6582. [link]
206.
Jiang, Y.; Krishnan, N.; Heo, J.; Fang, R.; Zhang, L.* "Nanoparticle-hydrogel superstructures for biomedical applications", Journal of Controlled Release 2020, 324, 505-521. [link]
205.
Zhang, Q.; Gong, H.; Gao, W.; Zhang, L.* "Recent progress in capturing and neutralizing inflammatory cytokines", CCS Chemistry 2020, 2, 376-389. [link]
204.
Zhuang, J.; Duan, Y.; Zhang, Q.; Gao, W.; Li, S.; Fang, R.; Zhang, L.* "Multimodal enzyme delivery and therapy enabled by cell membrane-coated metal-organic framework nanoparticles", Nano Letters 2020, 20, 4051-4058. [link]
203.
Zhou, J.; Kroll, A.; Holay, M.; Fang, R.; Zhang, L.* "Biomimetic nanotechnology toward personalized vaccines", Advanced Materials 2020, 32, 1901255. [link]
202.
Zhuang, J.; Gong, H.; Zhou, J.; Zhang, Q.; Gao W.; Fang, R.; Zhang, L.* "Targeted gene silencing in vivo by platelet membrane-coated metal-organic framework nanoparticles", Science Advances 2020, 6, eaaz6108. [link]
201.
Park, J. H.; Dehaini, D.; Zhou, J.; Holay, M.; Fang, R.; Zhang, L.* "Biomimetic nanoparticle technology for cardiovascular disease detection and treatment", Nanoscale Horizons 2020, 5, 25-42. [link]
2019
200.
Zhang, Y.; Miyamoto, Y.; Ihara, S.; Yang, J.; Zuill, D.; Angsantikul, P.; Zhang, Q.; Gao, W.; Zhang, L.*, Eckmann, L. "Composite thermoresponsive hydrogel with auranofin-loaded nanoparticles for topical treatment of vaginal trichomonad infection", Advanced Therapeutics 2019, 2, 1900157. [link]
199.
Wierzbicki, I.; Campeau, A.; Dehaini, D.; Holay, M.; Wei, X.; Greene, T.; Ying, M.; Sands, J.; Lamsa, A.; Zuniga, E.; Pogliano, K.; Fang, R.; LaRock, C.; Zhang, L.; Gonzalez, D. "Group A Streptococcal S protein utilizes red blood cells as immune camouflage and is a critical determinant for immune evasion", Cell Reports 2019, 29, 2979-2989. [link]
198.
Karshalev, E.; Zhang, Y.; Bsteban-Fernandez de Avila, B.; Beltran-Gastelum, M.; Chen, Y.; Mundaca-Uribe, R.; Zhang, F.; Nguyen, B.; Tong, Y.; Fang, R.; Zhang, L.*, Wang, J. "Micromotors for active delivery of minerals toward the treatment of iron deficiency anemia", Nano Letters 2019, 19, 7816-7826. [link]
197.
Koo, J.; Escajadillo, T.; Zhang, L.; Nizet, V.; Lawrence, S. M. "Erythrocyte-coated nanoparticles block cytotoxic effects of group B streptococcus beta-hemolysin/cytolysin", Frontiers in Pediatrics 2019, 7, 410. [link]
196.
Zhang, F.; Zhuang, J.; Bsteban-Fernandez de Avila, B.; Tang, S.; Zhang, Q.; Fang, R.; Zhang, L.*; Wang, J. "A nanomotor-based active delivery system for intracellular oxygen transport", ACS Nano 2019, 13, 11996-12005. [link]
195.
Zhuang, J.; Holay, M.; Park, J. H.; Fang, R.; Zhang, J.; Zhang, L.* "Nanoparticle delivery of immunostimulatory agents for cancer immunotherapy", Theranostics 2019, 9, 7826-7848. [link]
194.
Fang, R.; Zhang, L.* "Biomimetic nanosponges as a broad-spectrum countermeasure to biological threats", HDIAC Journal, 2019, 6(3), 14-19. [link] [journal cover]
193.
Zhang, Y.; Chen, Y.; Lo, C.; Zhuang, J.; Angsantikul, P.; Zhang, Q.; Wei, X.; Zhou, Z.; Obonyo, M.; Fang, R.; Gao, W.; Zhang, L.* "Inhibition of pathogen adhesion by bacterial outer membrane-coated nanoparticles", Angewandte Chemie International Edition 2019, 58, 11404-11408. [link]
192.
Kumar, S.; Han, J.; Michael, I.; Ki, D.; Sunkara, V.; Park, J.; Gautam, S.; Ha, H. K.; Zhang, L.; Cho, Y. "Human platelet membrane functionalized microchips with plasmonic codes for cancer detection", Advanced Functional Materials 2019, 29, 1902669. [link] [journal cover]
191.
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Pang, Z.; Hu, C-M. J.; Fang, R. H.; Luk, B. T.; Gao, W.; Wang, F.; Chuluun, E.; Angsantikul, P.; Thamphiwatana, S.; Lu, W.; Jiang, X.; Zhang, L.* "Detoxification of organophosphate poisoning using nanoparticle bioscavengers", ACS Nano 2015, 9, 6450-6458. [link]
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Wu, Z.; Li, T.; Gao, W.; Xu, T.; Jurado-Sanchez, B.; Li, J.; Gao, W.; He, Q.; Zhang, L.*; Wang, J. "Cell membrane-coated synthetic nanomotors for effective biodetoxification", Advanced Functional Materials 2015, 25, 3881-3887. [link]
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Wang, F.; Gao, W.; Thamphiwatana, S.; Luk, B.; Angsantikul, P.; Zhang, Q.; Hu, C-M.; Fang, R.; Copp, J.; Pornpattananangkul, D.; Lu, W.; Zhang, L.* "Hydrogel retaining toxin-absorbing nanosponges for local treatment of methicillin-resistant Staphylococcus aureus infection", Advanced Materials 2015, 27, 3437-3443. [link] [journal cover]
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Jung, S. W.; Thamphiwatana, S.; Zhang, L.*; Obonyo, M. "Mechanism of antibacterial activity of liposomal linolenic acid against Helicobacter pylori", PLOS ONE 2015, 10(3), e0116519. [link]
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Sanchez-Gaytan, B. L.; Fay, F.; Lobatto, M. E.; Tang, J.; Ouimet, M.; Kim, Y. T.; van der Staay, S.; van Rijs, S.; Priem, Z.; Zhang, L.; Fisher, E. A.; Moore, K.; Langer, R.; Fayad, Z. A.; Mulder, W. J. "HDL-mimetic PLGA nanoparticle for the targeting of atherosclerosis plaque macrophages", Bioconjugate Chemistry, 2015, 26, 443-451. [link]
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Gao, W.; Fang, R.; Thamphiwatana, S.; Luk, B.; Li, J.; Angsantikul, P.; Zhang, Q.; Hu, C-M.; Zhang, L.* "Modulating antibacterial immunity via bacterial membrane-coated nanoparticles", Nano Letters 2015, 15, 1403-1409. [link]
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Gao, W.; Dong, D.; Thamphiwatana, S.; Li, J.; Gao, W.; Zhang, L.*; Wang, J. "Artificial micromotors in the mouse's stomach: A step towards in vivo use of synthetic motors", ACS Nano 2015, 9, 117-123. [link]
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2014
90.
Wu, Z.; Li, T.; Li, J.; Gao, W.; Xu, T.; Christianson, C.; Gao, W.; Galarnyk, M.; He, Q.; Zhang, L.*; Wang, J. "Turning erythrocytes to functional micromotors", ACS Nano 2014, 8, 12041-12048. [link]
89.
Luk, B.; Zhang, L.* "Current advances in polymer-based nanotheranostics for cancer treatment and diagnosis", ACS Applied Materials & Interfaces 2014, 6, 21859-21873. [link]
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Thamphiwatana, S.; Gao, W.; Obonyo, M.; Zhang, L.* "In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation", Proceedings of the National Academy of Sciences 2014, 111, 17600-17605. [link]
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87.
Thamphiwatana, S.; Gao, W.; Pornpattananangkul, D.; Zhang, Q.; Fu, V.; Li, J.; Li, J.; Obonyo, M.; Zhang, L.* "Phospholipase A2-responsive antibiotic delivery via nanoparticle-stabilized liposomes for the treatment of bacterial infection", Journal of Materials Chemistry B 2014, 2, 8201-8207. [link]
86.
Gao, W.; Thamphiwatana, S.; Angsantikul, P.; Zhang, L.* "Nanoparticle approaches against bacterial infections", WIREs Nanomedicine & Nanobiotechnology 2014, 6, 532-547. [link]
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Copp, J.; Fang, R. Luk, B.; Hu, C-M.; Gao, W.; Zhang, K.; Zhang, L.* "Clearance of pathological antibodies using biomimetic nanoparticles", Proceedings of the National Academy of Sciences 2014, 111, 13481-13486. [link]
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84.
Hu, C-M.; Zhang, L.* "Nanotoxoid vaccines", Nano Today 2014, 9, 401-404. [link]
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Ouyang, H.; Xue, Y.; Lin, Y.; Zhang, X.; Xi, L.; Patel, S.; Cai, H.; Luo, J.; Zhang, M.; Zhang, M.; Yang, Y.; Li, G.; Li, H.; Jiang, W.; Yeh, E.; Lin, J.; Pei, M.; Zhu, J.; Cao, G.; Zhang, L.; Yu, B.; Chen, S.; Fu, X-D.; Liu, Y.; Zhang, K. "WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis", Nature 2014, 511, 358-361. [link]
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Yu, F-X.; Luo, J.; Mo, J-S.; Liu, G.; Kim, Y. C. ; Meng, Z.; Zhao, L.; Peyman, G.; Ouyang, H.; Jiang, W.; Chen, X.; Zhang, L.; Wang, C-Y.; Bastian, B. C.; Zhang, K.; Guan, K-L. "Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP", Cancer Cell 2014, 25, 822-830. [link]
80.
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Fang, R.; Hu, C-M.; Luk, B.; Gao, W.; Copp, J.; Tai, Y.; O'Connor, D.; Zhang, L.* "Cancer cell membrane-coated nanoparticles for anticancer vaccination and drug delivery", Nano Letters 2014, 14, 2181-2188. [link]
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Gao, W.; Vecchio, D.; Li, J.; Zhu, J.; Zhang, Q.; Fu, V.; Li, J.; Thamphiwatana, S.; Lu, D.; Zhang, L.* "Hydrogel containing nanoparticle-stabilized liposomes for topical antimicrobial delivery", ACS Nano 2014, 8, 2900-2907. [link]
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Luk, B.; Hu, C-M.; Fang, R.; Dehaini, D.; Carpenter, C.; Gao, W.; Zhang, L.* "Interfacial interactions between natural RBC membranes and synthetic polymeric nanoparticles", Nanoscale 2014, 6, 2730-2737. [link]
76.
Hu, J.; Zhu, S.; Xia, X.; Zhang, L.; Kleinerman, E. S.; Li, S. "CD8+T cell-specific induction of NKG2D receptor by doxorubicin plus interleukin-12 and its contribution on CD8+T cell accumulation in tumors", Molecular Cancer 2014, 13, 34. [link]
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Sukumar, R.; Sethi, M.; Karve, S.; Werner, M.; Moore, D.; Zhang, L.; Wang, A. Z. "Effect of drug release kinetics on nanoparticle therapeutic efficacy and toxicity", Nanoscale 2014, 6, 2321-2327. [link]
74.
Hu, C-M.; Fang, R.; Luk, B.; Zhang, L.* "Polymeric nanotherapeutics: clinical development and advances in stealth functionalization strategies", Nanoscale 2014, 6, 65-75. [link]
2013
73.
Hu, C-M.; Fang, R.; Luk, B.; Zhang, L.* "Nanoparticle-detained toxins for safe and effective vaccination",       Nature Nanotechnology 2013, 8, 933-938. [link]
Highlighted: Science 2013, 342, 1418. [link]
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72.
Gao, W.; Hu, C-M.; Fang, R.; Zhang, L.* "Liposome-like nanostructures for drug delivery", Journal of Materials Chemistry B, 2013, 1, 6569-6585. [link]
71.
Fang, R.; Hu, C-M.; Chen, K.; Luk, B.; Carpenter, C.; Gao, W.; Li, S.; Zhang, D-E.; Lu, W.; Zhang, L.* "Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles", Nanoscale 2013, 5, 8884-8888. [link]
70.
Pornpattananangkul, D.; Fu, V.; Thamphiwatana, S.; Zhang, L.; Chen, M.; Vecchio, J.; Gao, W.; Huang, C-M.; Zhang, L.* "In vivo treatment of Propionibacterium acnes infection with liposomal lauric acids", Advanced Healthcare Materials 2013, 2, 1322-1328. [link]
69.
Thamphiwatana, S.; Fu, V.; Zhu, J.; Lu, D.; Gao, W.; Zhang, L.* "Nanoparticle-stabilized liposomes for pH-responsive gastric drug delivery", Langmuir 2013, 29, 12228-12233. [link]
68.
Aryal, S.; Hu, C-M.; Fang, R.; Dehaini, D.; Carpenter, C.; Zhang, D-E.; Zhang, L.* "Erythrocyte membrane-cloaked polymeric nanoparticles for controlled drug loading and release", Nanomedicine 2013, 8, 1271-1280. [link]
67.
Gao, W.; Hu, C-M.; Fang, R.; Luk, B.; Su, J.; Zhang, L.* "Surface functionalization of gold nanoparticles with red blood cell membranes", Advanced Materials 2013, 25, 3549-3553. [link] [journal cover]
66.
Hu, C-M.; Fang, R.; Copp, J.; Luk, B.; Zhang, L.* "A biomimetic nanosponge that absorbs pore-forming toxins", Nature Nanotechnology 2013, 8, 336-340. [link] [animation]
Highlighted: Science Translational Medicine 2013, 5 (184), 184ec78. [link]
                    Nano Today, 2013, 8, 217-218. (News and Opinions) [link]
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65.
Hu, C-M.; Fang, R.; Luk, B.; Chen, K.; Carpenter, C.; Gao, W.; Zhang, K.; Zhang, L.* "'Marker-of-self' functionalizaton of nanoscale particles through a top-down cellular membrane coating approach", Nanoscale 2013, 5, 2664-2668. [link]
64.
Kong, S.; Sartor, M.; Hu, C-M.; Zhang, W.; Zhang, L.*; Jin, S. "Magnetic field activated lipid-polymer hybrid nanoparticles for stimuli-responsive drug release", Acta Biomaterialia 2013, 9, 5447-5452. [link]
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Zhao, J.; Sun, W.; Cho, H. M.; Ouyang, H.; Li, W.; Lin, Y.; Do, J.; Zhang, L.; Ding, S.; Liu, Y.; Lu, P.; Zhang, K. "Integration and long distance axonal regeneration in the central nervous system from transplanted primitive neural stem cells", Journal of Biological Chemistry 2013, 288, 164-168. [link]
2012
62.
Gao, W.; Zhang, L.* "Unleash the forces within", Nature Chemistry 2012, 4, 971-972. [link]
61.
Luk, B. T.; Fang, R. H.; Zhang, L.* "Lipid- and polymer-based nanostructures for cancer theranostics", Theranostics 2012, 2, 1117-1126. [link]
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Fang, R.; Chen, K.; Aryal, S.; Hu, C-M.; Zhang, K.; Zhang, L.* "Large-scale synthesis of lipid-polymer hybrid nanoparticles using a multi-inlet vortex reactor", Langmuir 2012, 28, 13824-13829. [link]
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Hu, C-M.; Fang, R. H.; Zhang, L.* "Erythrocyte-inspired delivery systems", Advanced Healthcare Materials      2012, 1, 537-547. [link]
58.
Obonyo, M.; Zhang, L.; Thamphiwatana, S.; Pornpattananangkul, D.; Fu, V.; Zhang, L.* "Antibacterial activities of liposomal linolenic acids against antibiotic-resistant Helicobacter pylori", Molecular Pharmaceutics 2012, 9, 2677-2685. [link]
57.
Shaw, P. X.; Zhang, L.; Zhang, M.; Du, H.; Zhao, L.; Lee, C.; Crob, S.; Lim, S. L.; Hughes, G.; Lee, J.; Bedell, M.; Nelson, M. H.; Lu, F.; Luo, J.; Ouyang, H.; Tu, Z.; Su, Z.; Zhu, J.; Wei, X.; Feng, Z.; Duan, Y.; Yang, Z.; Ferreyra, F.; Bartsch, D-U.; Kozak, I.; Zhang, L.; Lin, F.; Sun, H.; Feng, H.; Zhang, K. "Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids", Proceedings of the National Academy of Sciences 2012, 109, 13757-13762. [link]
56.
Zhang, K.; Zhang, L.; Weinreb, R. N. "Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma", Nature Reviews Drug Discovery 2012, 11, 541-559. [link]
55.
Fang, R. H.; Hu, C-M.; Zhang, L.* "Nanoparticles disguised as red blood cells to evade the immune system", Expert Opinion on Biological Therapy 2012, 12, 385-389. [link]
54.
Aryal, S.; Hu, C-M.; Zhang, L.* "Synthesis of Ptsome: A platinum-based liposome-like nanostructure", Chemical Communications 2012, 48, 2630-2632. [link]
53.
Hu, C-M.; Zhang, L.* "Nanoparticle-based combination therapy toward overcoming drug resistance in cancer", Biochemical Pharmacology 2012, 83, 1104-1111. [link]
52.
Gao, W.; Kagan, D.; Pak, O. ; Clawson, C.; Campuzano, S.; Erdene, E. C.; Fullerton, E.; Zhang, L.*; Lauga, E.; Wang, J. "Cargo-towing fuel-free magnetic nanomotors for targeted drug delivery", Small 2012, 8, 460-467. [link]
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Aryal, S.; Hu, C-M.; Fu, V.; Zhang, L.* "Nanoparticle drug delivery enhances the cytotoxicity of hydrophobic- hydrophilic drug conjugates", Journal of Materials Chemistry 2012, 22, 994-999. [link]
2011
50.
Clawson, C.; Ton, L.; Aryal, S.; Fu, V.; Esener, S.; Zhang, L.* "Synthesis and characterization of lipid-polymer hybrid nanoparticles with pH-triggered PEG shedding", Langmuir 2011, 27, 10556-10561. [link]
49.
Fang, R. H.; Zhang, L.* "Dispersion-based methods for the engineering and manufacture of polymeric nanoparticles for drug delivery applications", Journal of Nanoengineering and Nanomanufacturing 2011, 1, 106-112. [link]
48.
Aryal, S.; Hu, C-M.; Zhang, L.* "Polymeric nanoparticles with precise ratiometric control over drug loading for combination therapy", Molecular Pharmaceutics 2011, 8, 1401-1407. [link]
47.
Hu, C-M.; Zhang, L.; Aryal, S.; Cheung, C.; Fang, R. H.; Zhang, L.* "Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform", Proceedings of the National Academy of Sciences 2011, 108, 10980-10985. [link]
Highlighted: Nano Today 2011, 6, 327. (News and Opinions) [link]
                    National Academy of Engineering, "Engineering Innovation" Radio News [link]
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Balasubramanian, S.; Kagan, D.; Hu, C-M.; Campuzano, S.; Lobo-Castañon, M. J.; Lim, N.; Kang, D.; Zhang, L.*; Wang, J. "Nanomachine enabled selection and isolation of cancer cells in complex media", Angewandte Chemie International Edition 2011, 50, 4161-4164. [link] [journal cover]
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Chen, C-H.; Wang, Y.; Liu, Y-T.; Zouboulis, C.; Gallo, R. L.; Zhang, L.*; Hsieh, M-F.; Huang, C-M. "An innate bactericidal oleic acid effective against skin infection of methicillin-resistant Staphylococcus aureus: a therapy concordant with evolutionary medicine", Journal of Microbiology and Biotechnology 2011, 21, 391-399. [link]
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Nakatsuji, T.; Tang, D-C.; Zhang, L.; Gallo, R. L.; Huang, C-M. "Propionibacterium acnes CAMP factor and host acid sphingomyelinase contribute to bacterial virulence: potential targets for inflammatory acne treatment",
PLOS ONE 2011, 6(4), e14797. [link]
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Pornpattananangkul, D.; Zhang, L.; Olson, S.; Aryal, S.; Obonyo, M.; Vecchio, K.; Huang, C-M.; Zhang, L.* "Bacterial toxin-triggered drug release from gold nanoparticle-stabilized liposomes for the treatment of bacterial infection", Journal of the American Chemical Society 2011, 133, 4132-4139. [link]
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Clawson, C.; Esener, S.; Zhang, L.* "Lipid-Polymer Nanomaterials" in Polymeric Nanomaterials (Kumar, C., Ed), Wiley-VCH Press, 2011, 259-284.
41.
Huang, C-M.; Chen, C-H.; Pornpattananangkul, D.; Zhang, L.; Chan, M.; Hsieh, M-F.; Zhang, L.* "Eradication of drug resistant Staphylococcus aureus by liposomal oleic acids", Biomaterials 2011, 32, 214-221. [link]
2010
40.
Kagan, D.; Laocharoensuk, R.; Zimmerman, M.; Clawson, C.; Balasubramanian, S.; Kang, D.; Bishop, D.; Sattayasamitsathit, S.; Zhang, L.*; Wang, J. "Rapid delivery of drug carriers propelled and navigated by catalytic nanoshuttles", Small 2010, 6, 2741-2747. [link]
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Fang, R. H.; Aryal, S.; Hu, C-M.; Zhang, L.* "Quick synthesis of lipid-polymer hybrid nanoparticles with low polydispersity using a single-step sonication method", Langmuir 2010, 26, 16958-16962. [link]
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Zhang, L.; Zhang, L*"Lipid-polymer hybrid nanoparticles: synthesis, characterization and applications",
Nano LIFE 2010, 1, 163-173. [link]
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Hu, C-M.; Aryal, S.; Zhang, L.* "Nanoparticles assisted combination therapies for effective cancer treatment", Therapeutic Delivery 2010, 1, 323-334. [link]
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Aryal, S.; Hu, C-M.; Zhang, L.* "Combinatorial drug conjugation enabled nanoparticle dual drug delivery",
Small 2010, 6, 1442-1448. [link]
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Chumbimuni-Torres, K. Y.; Wu, J.; Clawson, C.; Galik, M.; Walter, A.; Flechsig, G-U.; Bakker, E.; Zhang, L.*; Wang, J. "Amplified potentiometric transduction of DNA hybridization using ion-loaded liposomes", Analyst 2010, 135, 1618-1623. [link]
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Hu, C-M,; Kaushal, S.; Tran Cao, H. S.; Aryal, S.; Sartor, M.; Esener, S.; Bouvet, M.; Zhang, L.* "Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells", Molecular Pharmaceutics 2010, 7, 914-920. [link]
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Pornpattananangkul, D.; Olson, S.; Aryal, S.; Sartor, M.; Huang, C-M.; Vecchio, K. S.; Zhang, L.* "Stimuli-responsive liposome fusion mediated by gold nanoparticles", ACS Nano 2010, 4, 1935-1942. [link]
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Wang, A.; Yuet, K.; Zhang, L.; Gu, F.; Huynh-Le, M.; Radovic-Moreno, A.; Langer, R.; Farokhzad, O. C. "ChemoRad nanoparticles: A novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation", Nanomedicine 2010, 5, 361-368. [link]
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Valencia, P.; Basto, P., Zhang, L.; Rhee, M.; Langer, R.; Farokhzad, O. C.; Karnik, R. "Single-step assembly of homogeneous lipid-polymeric and lipid-quantum dots nanoparticles enabled by microfluidic rapid mixing",
ACS Nano 2010, 4, 1671-1679. [link]
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Nakatsuji, T.; Kao, M. C.; Zhang, L.; Zouboulis, C. C.; Gallo, R. L.; Huang, C-M. "Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating ß-defensin-2 expression", Journal of Investigative Dermatology 2010, 130, 985-994. [link]
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Chan, J.; Zhang, L.; Tong, R.; Ghosh, D.; Gao, W.; Liao, G.; Yuet, K.; Gray, D.; Rhee, J-W.; Cheng, J.; Golomb, G.; Libby, P.; Langer, R.; Farokhzad, O. C. "Spatiotemporal controlled delivery of nanoparticles to injured vasculature", Proceedings of the National Academy of Sciences 2010, 107, 2213-2218. [link]
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Chan, J.; Valencia, M. P.; Zhang, L.; Langer, R.; Farokhzad, O. C. "Polymer nanoparticles for drug delivery" in Cancer Nanotechnology: Methods and Protocols (Grobmyer, S. and Moudgil, B., Eds.), Springer Press, USA, 2010, 163-175. [link]
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Aryal, S.; Hu, C-M.; Zhang, L.* "Polymer-cisplatin conjugate nanoparticles for acid-responsive drug delivery",
ACS Nano 2010, 4, 251-258. [link]
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Zhang, L.*; Pornpattananangkul, D.; Hu, C-M.; Huang, C-M. "Development of nanoparticles for antimicrobial drug delivery", Current Medicinal Chemistry 2010, 17, 585-594. [link]
2009
25.
Hu, C-M.; Zhang, L.* "Therapeutic nanoparticles to combat cancer drug resistance", Current Drug Metabolism 2009, 10, 836-841. [link]
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Mora, L.; Chumbimuni-Torres, K. Y.; Clawson, C.; Hernandez, L.; Zhang, L.*; Wang, J. "Real-time electrochemical monitoring of drug release from therapeutic nanoparticles", Journal of Controlled Release 2009, 140, 69-73. [link]
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Yang, D.; Pornpattananangkul, D.; Nakatsuji, T.; Chan, M.; Carson, D.; Huang, C-M.; Zhang, L.* "The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes", Biomaterials 2009, 30, 6035-6040. [link]
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Nakatsuji, T.; Kao, M. C.; Fang, J-Y.; Zouboulis, C. C.; Zhang, L.; Gallo, R. L.; Huang, C-M. "Antimicrobial property of lauric acid against propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris",
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Salvador-Morales, C.; Zhang, L.; Langer, R.; Farokhzad, O. C. "Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups", Biomaterials 2009, 30, 2231-2240. [link]
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Chan, J.; Zhang, L.; Yuet, K.; Liao, G.; Rhee, J-W.; Langer, R.; Farokhzad, O. C. "PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery", Biomaterials 2009, 30, 1627-1634. [link]
2008
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Alexis, F.; Basto, P.; Levy-Nissenbaum, E.; Radovic-Moreno, A.; Zhang, L.; Pridgen, E.; Wang, A.; Molnar, S.; Westerhof K.; Farokhzad, O. C. "HER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy", ChemMedChem 2008, 3, 1839-1843. [link]
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Wang, B.; Zhang, L.; Bae, S. C.; Granick, S. "Nanoparticle-induced surface reconstruction of phospholipid membranes", Proceedings of the National Academy of Sciences 2008, 105, 18171-18175. [link]
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Wang, A.; Bagalkot, V.; Vasilliou, C.; Gu. F.; Alexis, F.; Zhang, L.; Shaikh, M. R.; Yuet, K.; Cima, M.; Langer, R.; Kantoff, P. W.; Bander, N. H.; Jon, S.; Farokhzad, O. C. "Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy", ChemMedChem 2008, 3, 1311-1315. [link]
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Zhang, L. ; Chan, J.; Gu, F.; Rhee, J-W.; Wang, A.; Radovic-Moreno, A.; Alexis, F.; Langer, R.; Farokhzad, O. C. "Self-assembled lipid-polymer hybrid nanoparticles: A robust drug delivery platform", ACS Nano 2008, 2, 1696-1702. [link]
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Wang, A.; Gu, F.; Zhang, L.; Chan, J.; Radovic-Modovic, A.; Shaikh, M. R.; Farokhzad, O. C. "Biofunctionalized targeted nanoparticles for therapeutic applications", Expert Opinion on Biological Therapy 2008, 8, 1063-1070. [link]
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Zhang, L.; Gu, F.; Chan, J.; Wang, A.; Langer, R.; Farokhzad, O. C. "Nanoparticles in medicine: Therapeutic applications and developments", Clinical Pharmacology & Therapeutics 2008, 83, 761-769. [link]
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Gu, F.; Zhang, L.; Teply, B.; Mann, N.; Wang, A.; Radovic-Moreno, A.; Langer, R.; Farokhzad, O. C. "Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers",
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2007
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Bagalkot, V.; Zhang, L.; Levy-Nissenbaum, E.; Jon, S.; Kantoff, P. W.; Langer, R.; Farokhzad, O. C. "Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy and sensing of drug delivery based on bi-fluorescence resonance energy transfer", Nano Letters 2007, 7, 3065-3070. [link]
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Zhang, L.; Radovic-Moreno, A.; Alexis, F.; Gu, F.; Basto, P. A.; Bagalkot, V.; Jon, S.; Langer, R.; Farokhzad, O. C. "Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates", ChemMedChem 2007, 2, 1268-1271. [link]
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Yu, Y.; Anthony, S.; Zhang, L.; Bae, S. C.; Granick, S. "Cationic nanoparticles stabilize zwitterionic liposomes better than anionic ones", Journal of Physical Chemistry C 2007, 111, 8233-8236. [link]
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Zhang, L.; Dammann, K.; Bae, S. C. Granick, S. "Ligand-receptor binding on nanoparticle-stabilized liposome surfaces", Soft Matter 2007, 3, 551-553. [link]
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Zhang, L.; Granick, S. "Inter-leaflet diffusion coupling when polymer adsorbs onto one sole leaflet of a supported phospholipid bilayer", Macromolecules 2007, 40, 1366-1368. [link]
2006
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Zhang, L.; Hong, L.; Yu, Y.; Bae, S. C.; Granick, S. "Nanoparticle-assisted surface immobilization of phospholipid liposomes", Journal of the American Chemical Society 2006, 128, 9026-9027. [link]
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Zhang, L.; Granick, S. "Dynamical heterogeneity in supported lipid bilayers", MRS Bulletin 2006, 31, 527-531. [link]
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Anthony, S.; Zhang, L.; Granick, S. "Methods to track single-molecule trajectories", Langmuir 2006, 22, 5266-5272. [link]
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Zhang, L.; Granick, S. "How to stabilize phospholipid liposomes (using nanoparticles)", Nano Letters 2006, 6, 694-698. [link]
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Zhang, L.; Spurlin, T. A.; Gewirth, A. A.; Granick, S. "Electrostatic stitching in gel-phase supported phospholipid bilayers", Journal of Physical Chemistry B 2006, 110, 33-35. [link]
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2005
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Zhang, L.; Granick, S. "Lipid diffusion compared in outer and inner leaflets of planar supported bilayers",
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Zhang, L.; Granick, S. "Slaved diffusion in phospholipid bilayers", Proceedings of the National Academy of Sciences 2005, 102, 9118-9121. [link]